Garcinia Cambogia Side Effects to Liver?

There is some concern that Garcinia Cambogia may have side effects on the liver. Here is what we’ve found on this.

The Natural Products Database overview for Garcinia Cambogia extract / Hydroxycitric Acid states that toxicology studies resulted in no toxicity or deaths in animals at doses of HCA 5000 mg/kg – equivalent to about 350 g of HCA, or 233 times the maximum recommend dosage of 1500 mg / day of HCA.


There is concern about people taking certain combination weight loss supplements and the possibility of severe or fatal hepatotoxicity developing. Hepatotoxicity implies “chemical driven liver damage” according to wikipedia.org.

The combination-ingredient product in question, which may have contained up to 20 different ingredients, was an older verison of the popular Hydroxycut and it was subsequently removed from the market. But, there is also a lot of research suggesting there is no evidence demonstrating that hepatotoxicity developed was associated with hydroxycitric acid / HCA derived from garcinia cambogia rind.

There was one case of fatal liver failure where someone was taking Singulair and two other dietary supplements, one which contained garcinia. It is unclear from my research whether this is the same case as the Hydroxycut / hepatotoxicity case mentioned above.

So, use your judgement or consult your doctor as needed, but it is generally believed that the isolated case was due to either the combination or other ingredients all together, and that the garcinia cambogia extract side effects to the liver are not an issue when taking at the recommend doses.

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